ABSTRACT
Con el avance de la pandemia por COVID-19, la aparición de pacientes con un segundo episodio confirmado por reacción en cadena de la polimerasa, con transcripción inversa (rt-PCR) compatible con reinfección, puso de manifiesto la falta de recomendaciones para su abordaje.Presentamos un estudio descriptivo multicéntrico retro-prospectivo de una serie de doce casos atendidos entre el 01/06/2020 y el 20/10/2020. En la misma, diez casos presentaron el segundo episodio en un período de tiempo menor a 90 días.Por su complejidad, la confirmación de una reinfección no está al alcance en la práctica diaria. Esto requiere de estudios que incluyan comparaciones genómicas de cepas virales involucradas en ambos episodios, determinación de la infectividad del ARN por cultivo viral y análisis molecular.Es necesario establecer definiciones operativas y algoritmos clínicos para la atención de los segundos episodios
As COVID-19 pandemic progresses, patients with a second confirmed episode by reverse transcription-polymerase chain reaction (RT PCR) compatible with reinfection reveals the lack of recommendations for its approach.A multicenter retro-prospective descriptive work was done of a series of 12 cases evaluated between June 1, 2020 and October 20, 2020. In this study, 10 out of 12 cases presented the second episode occurred in less than 90 days.Due to the diagnosing reinfection complexity, its confirmation is not available in the daily practice, this requires studies, which include viral strains genomic comparisons involved in both episodes, ARN determination infectivity by viral culture and molecular analysis.It is necessary to establish operational and clinical algorithms definitions to assist second episodes
Subject(s)
Humans , Adult , Middle Aged , Aged , Epidemiology, Descriptive , Retrospective Studies , Multicenter Study , Virus Shedding , Decision Making , Ambulatory Care , Reinfection/therapy , Coronavirus RNA-Dependent RNA Polymerase/immunology , HospitalizationABSTRACT
En Argentina, las especies de arañas de importancia sanitaria pertenecen a los géneros Loxosceles, Phoneutria y Latrodectus. El objetivo del presente trabajo fue relevar los accidentes producidos por el género Latrodectus atendidos en el centro de referencia y derivación provincial de animales venenosos de Jujuy (Hospital San Roque) en el período: 1 de enero de 1998 al 31 de diciembre de 2014. En los diecisiete años analizados se registraron 30 historias clínicas con diagnóstico de latrodectismo, el 83 % de los casos procede de zonas semiáridas y áridas de la provincia de Jujuy. Se registró un valor medio de 1.8 casos/año; la mayoría de los accidentados (63 %) fueron de sexo masculino y la franja etaria más afectada se ubicó entre 16-25 años (50 %). La visualización del arácnido fue confirmada por 18 pacientes, de los cuales el 67 % (n=12) lo identificó como "huayruro" o "viuda negra". Entre las manifestaciones clínicas predominaron: dolor local, dolor generalizado, dolor abdominal, diaforesis e hipertensión arterial. El periodo de internación fue corto (2,7 días) y no hubo complicaciones ni óbitos. Este es el primer estudio clínico-epidemiológico de latrodectismo en el noroeste argentino.
In Argentina, the species of spiders of sanitary importance belong to the Loxosceles, Latrodectus and Phoneutria genera. The objective of this study was to survey accidents caused by the spiders of Latrodectus genus treated at the Jujuy provincial venomous animal reference and referral center (San Roque Hospital) between January 1, 1998 and December 31, 2014. In the seventeen years analyzed, 30 medical records with a diagnosis of latrodectism were analyzed, 83% of the cases came from semi-arid and arid areas of the province of Jujuy. An average of 1.8 cases/year was established. Most of the injured (63%) were male and the most affected age group was between 16-25 years (50%). The arachnid depiction was confirmed by 18 patients, of which 67% (n=12) identified it as "huayruro" or "black widow". Predominant clinical manifestations were local pain, generalized pain, abdominal pain, diaphoresis and hypertension. The length of hospitalization was short (2,7 days) and there were no complications or deaths. This is the first clinical-epidemiological study of latrodectism in northwestern Argentina
Subject(s)
Humans , Male , Female , Adolescent , Adult , Black Widow Spider , Spider Bites/epidemiology , Argentina/epidemiology , Spider VenomsABSTRACT
Tick paralysis (TP) occurs worldwide and is caused by a neurotoxin secreted by engorged female ticks that affects the peripheral and central nervous system. The clinical manifestations range from mild or nonspecific symptoms to manifestations similar to Guillain-Barré syndrome, bulbar involvement, and death in 10% of the patients. The diagnosis of TP is clinical. To our knowledge, there are no formal reports of TP in humans in South America, although clusters of TP among hunting dogs in Argentina have been identified recently. In this paper, clinical features of two cases of TP occurring during 1994 in Jujuy Province, Argentina, are described.
A paralisia por carrapatos (PC) ocorre mundialmente e é causada por uma neurotoxina secretada por carrapatos fêmea engolidores de sangue que afeta o sistema nervoso periférico e central. As manifestações clínicas variam de suave ou sintomas não específicos a manifestações semelhantes à síndrome de Guillain-Barré, envolvimento de bulbar, e morte em 10% dos pacientes. O diagnóstico de PC é clínico. A nosso conhecimento, não há nenhum relatório formal em seres humanos na América do Sul, embora grupos de PC entre cães de caça na Argentina, tenham sido identificados recentemente. Neste artigo, descrevo dois casos de PC ocorridos durante o ano de 1994 na província de Jujuy, Argentina.